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Aaron M. Bender
Former Member
UofM Directory
Finger Information
Phone: (734) 764-7338
ambender@umich.edu
 
B.S.:
Albion College, Albion MI
 

Research Interests

Design and synthesis of opioid peptidomimetics


Selected Publications

Harland A.A., Bender A.M., Griggs N.W., Gao C., Anand J.P., Pogozheva I.D., Traynor J.R., Jutkiewicz E.M., Mosberg H.I.
Effects of N-substitutions on the tetrahydroquinoline (THQ) core of mixed-efficacy mu-opioid receptor (MOR)/delta-opioid receptor (DOR) ligands
J Med Chem, 59: 4985-4998 (2016)

 

Bender A.M., Griggs N.W., Anand J.P., Traynor J.R., Jutkiewicz E.M., Mosberg H.I.
Asymmetric synthesis and in vitro and in vivo activity of tetrahydroquinolines featuring a diverse set of polar substitutions at the 6 position as mixed-efficacy mu opioid receptor/delta opioid receptor ligands
ACS Chem Neurosci, 6: 1428-1435 (2014)

 

Bender A.M., Clark M.J., Agius M.P., Traynor J.R., Mosberg H.I.
Synthesis and evaluation of 4-substituted piperidines and piperazines as balanced affinity mu opioid receptor (MOR) agonist/delta opioid receptor (DOR) antagonist ligands
Bioorg Med Chem Lett, 24: 548-551 (2014)

 

Mosberg H.I., Yeomans L., Harland A.A., Bender A.M., Sobczyk-Kojiro K., Anand J.P., Clark M.J., Jutkiewicz E.M., Traynor J.R.
Opioid peptidomimetics: leads for the design of bioavailable mixed efficacy mu opioid receptor (MOR) agonist/delta opioid receptor (DOR) antagonist ligands
J Med Chem, 56: 2139-2149 (2013)

 

People People
Henry I. Mosberg
Andrei L.Lomize
Irina D.Pogozheva
Katarzyna Sobczyk-Kojiro
Jessica Anand
Anthony F. Nastase
Sean P. Henry
Deanna Montgomery
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